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I Posted Before But Not In Question Form. Is Beta 2 Microglobulin The Same As M Spike? Mine Is 3rd Highest After 4 Years 4.12.

A MyMyelomaTeam Member asked a question 💭
Cathedral City, CA

I am feeling good and had about 3 IGIG IV'S this year. What is going on.

August 4
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A MyMyelomaTeam Member

No, they are two different tests.

August 5
A MyMyelomaTeam Member

Beta-2 microglobulin and M spike are not the same.

- Beta-2 Microglobulin Test: This test looks for the presence of beta-2 microglobulin, a protein found on the surface of many cells, including myeloma cells. High levels can indicate a higher tumor burden and are used to assess the prognosis of multiple myeloma.

- M Show Full Answer

Beta-2 microglobulin and M spike are not the same.

- Beta-2 Microglobulin Test: This test looks for the presence of beta-2 microglobulin, a protein found on the surface of many cells, including myeloma cells. High levels can indicate a higher tumor burden and are used to assess the prognosis of multiple myeloma.

- M Spike: Also known as monoclonal protein or M protein, this is detected through tests like serum protein electrophoresis (SPEP). It measures the level of abnormal monoclonal antibodies produced by myeloma cells.

Your Beta-2 microglobulin level of 4.12 being the third highest after four years suggests a significant tumor burden, and it is important to discuss this with your healthcare provider for appropriate management.

August 4

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