To diagnose multiple myeloma, doctors use various clinical tests and findings. Here are the key diagnostic criteria and tests:

Diagnostic Criteria
- Abnormal Plasma Cells: 60% or more of the cells in the bone marrow are abnormal plasma cells.
- Abnormal Light Chains: High levels of abnormal light chains (proteins Show Full Answer

To diagnose multiple myeloma, doctors use various clinical tests and findings. Here are the key diagnostic criteria and tests:

Diagnostic Criteria:
- Abnormal Plasma Cells: 60% or more of the cells in the bone marrow are abnormal plasma cells.
- Abnormal Light Chains: High levels of abnormal light chains (proteins produced by abnormal plasma cells).
- Lesions: More than one lesion visible in MRI studies.
- Organ Damage: Evidence of organ damage such as high calcium levels, anemia, kidney failure, or bony lesions shown on imaging tests.
- Biopsy: A biopsy showing that 10% or more of a person’s bone marrow cells are abnormal plasma cells.

Tests and What They Show:
- Blood and Urine Tests: Can reveal anemia, high calcium levels, elevated creatinine and urea nitrogen levels, low albumin levels, and elevated beta-2 microglobulin levels.
- Imaging Tests: X-rays, MRI scans, and PET scans to view abnormalities and bone damage.
- Bone Marrow Biopsy: To check for abnormal plasma cells.

Symptoms Leading to Diagnosis:
- Back pain
- Bone pain
- Frequent infections
- Fatigue

Staging:
- Multiple myeloma is assigned a stage to determine the best treatment options.

For more detailed information, you can visit the source: [Multiple Myeloma – The Path to Diagnosis](https://www.mymyelomateam.com/resources/multipl...).

 This AI-generated response comes from MyMyelomaTeam and other selected sources. It is not a substitute for medical advice. Always ask your doctor about specific health concerns.

Multiple Myeloma – The Path to Diagnosis | MyMyelomaTeam

Tests for Multiple Myeloma | MyMyelomaTeam