Hi Larry, I had a plasmacytoma on the top of my humerus. It ate away the whole humeral head and ended up causing the humerus to fracture. It was how I found out I had MM. An orthopedic surgeon pounded a hollow rod into the bone and secured it with screws. It is called nailing the humerus. It was extremely painful. I did not have radiation. The darzalex fast pro, Velcade, Revlimid and dexamethasone took care of the plasmacytoma. The bone grew back overtime. It is not as even as the original bone but it is ok. I lost a lot of function in my right arm. It is weaker and I have reduced range of motion. I am glad I did not have radiation and that the drugs took care of it. After healing, I am pain free. I also get zometa every three months.

Good luck with your treatment.

Radiation will kill the MM and my IgA and MSpike and all related Labs problems will get much better. Radiation is best for a single Spot. If that is the case, I was advised I would not need a Full Induction. Reading my PET/CT Report, there's small lesions in multiple locations. In this case, Chemo (Revlimid, Dex, DarzFasPro) is required to reach the MM everywhere. Based on the size of the one large lesion at the top of my humerus bone, radiation for it may be best for it.

I'm having a Consult with a Specialist on Friday as well as meeting with my local oncologist. Since my Numbers are rapidly coming down from just one week's treatment, the radiation may not be needed. Radiation would take weeks and is capable of residual side effects. Also the location of the lesion may be risky for other organs to receive radiation.

Hi GailD -So sorry to hear of your bone event. I believe I caught mine soon enough. I'll know in a week or two. Waiting for my PET/CT report. I'll be getting a Skeletal Survey next week.

My recent MRI report said "thinning but no risk of fracture or breakage".

Just got my MSpike from one week of Revlimid + Dex (pre-first DarzFasPro shot). Already down from 1.0 to 0.65 and IgA down from 1400 to 900. Getting my second DarzFP shot on Friday.

Being that it was isolated to my humerus bone, my Labs were not showing the magnitude of the activity (a 10.0 quake).

I received monthly Zometa infusions for 2 yrs to repair lesions in left hip iliac, ribs, sternum, and one vertebra after initial 12 radiation treatments. Have also been taking Vitamin D and calcium ever since. Had MM start reoccurring in sternum 4 yrs later and had more radiation treatment but didn’t need to restart Zometa treatments. MM doesn’t progress in a straight line. Just have to adapt as it throws another curve.

Larry,
I just took a deep breath and let it out. What a relief to hear your good news. Your good news gives the rest of us hope and guidance.💕
Paula 🌹