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Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Bone Lesions

A MyMyelomaTeam Member asked a question 💭
Oceanside, CA

Has anyone had many bone lesions -- and then had SCT? Does SCT help prevent the development of more lesions, or not necessarily?

May 10
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A MyMyelomaTeam Member

I’m not sure but the eradication of the MM cells should stop all bone lesions. I had lesions in several bone areas and even on the liver in four places. The induction chemo and the ASCT eliminated all traces of lesions as verified by the PET scan.

Now maintenance chemo keeps the aggressive MM in check but I still need a bone strengthening shot of Xgeva monthly.

Hopefully this helps Teresa!

May 10
A MyMyelomaTeam Member

Yes. Active disease is what damages bones. Thankfully I just had one significant lesion, 2x3cm in pelvis. The bone booster Zometa and Xgevia caused trouble for me, so I supplement and exercise for my bones which are otherwise healthy and pain free. Best, Leila

May 11
A MyMyelomaTeam Member

Active myeloma can cause bone lesions. So if it stays controlled there is a better chance to keep bones. I have been told if there is relapse to return to zometa or xgeva to help protect the bones.

May 10
A MyMyelomaTeam Member

Bone lesions in multiple myeloma are areas where the bone has been damaged due to the growth of cancerous plasma cells in the bone marrow. These lesions can weaken the bones, making them more susceptible to fractures and causing significant pain. Here are some key points about bone lesions in multiple myeloma:

- Osteolytic Show Full Answer

Bone lesions in multiple myeloma are areas where the bone has been damaged due to the growth of cancerous plasma cells in the bone marrow. These lesions can weaken the bones, making them more susceptible to fractures and causing significant pain. Here are some key points about bone lesions in multiple myeloma:

- Osteolytic Lesions: These are soft spots or areas of bone loss within the skeletal structure, commonly seen in multiple myeloma patients.
- Symptoms: The primary symptom of bone lesions is pain, which can be severe and debilitating. The pain often increases with activity and can significantly impact the quality of life.
- Treatment Options:
- Radiation Therapy: This can be used to target and treat individual osteolytic lesions, especially when they cause significant pain.
- Bisphosphonates: These medications are used to treat multiple areas affected by lesions, helping to manage pain and prevent further bone damage.
- Impact on Patients: The presence of bone lesions often exacerbates the distress of patients, especially when they learn about the need for comprehensive treatments like chemotherapy or surgery.

Managing bone lesions effectively is crucial for improving the overall well-being and quality of life for those affected by multiple myeloma.

May 10

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