Light chains are a component of immunoglobulins (antibodies) produced by plasma cells. In the context of multiple myeloma, here are some key points about light chains:

- Types of Light Chains: There are two types of light chains, kappa and lambda
- Light Chain Multiple Myeloma: About 20% of people with multiple myeloma Show Full Answer

Light chains are a component of immunoglobulins (antibodies) produced by plasma cells. In the context of multiple myeloma, here are some key points about light chains:

- Types of Light Chains: There are two types of light chains, kappa and lambda.
- Light Chain Multiple Myeloma: About 20% of people with multiple myeloma are diagnosed with light chain multiple myeloma, also known as Bence-Jones myeloma. In this condition, plasma cells produce only the light chain component of abnormal immunoglobulins.
- Symptoms: Symptoms of light chain multiple myeloma are similar to other types of myeloma and include bone damage, gastrointestinal and urinary problems, and neurological symptoms.
- Diagnosis: A serum free light chain assay is used to detect excess light chains in the blood. A serum free light chain ratio of 100 or more can specifically diagnose light chain multiple myeloma.
- Prognosis: Identifying the type of abnormal antibody produced can help estimate prognosis and risk of relapse.

For more detailed information, you can refer to the resources provided in my knowledge base.

 This AI-generated response comes from MyMyelomaTeam and other selected sources. It is not a substitute for medical advice. Always ask your doctor about specific health concerns.

Light Chain Multiple Myeloma: Your Ultimate Guide | MyMyelomaTeam

IgG and IgA Antibodies: What Do They Mean? | MyMyelomaTeam