No, M protein is not simply the sum of kappa and lambda paraproteins. M protein, also known as myeloma protein, monoclonal protein, M spike, or paraprotein, is produced by abnormal plasma cells. These proteins are monoclonal immunoglobulins, meaning they are identical antibodies produced by cloned abnormal plasma cells.

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No, M protein is not simply the sum of kappa and lambda paraproteins. M protein, also known as myeloma protein, monoclonal protein, M spike, or paraprotein, is produced by abnormal plasma cells. These proteins are monoclonal immunoglobulins, meaning they are identical antibodies produced by cloned abnormal plasma cells.

Here are some key points about M protein:

- M Protein: Made by abnormal plasma cells.
- Types of Heavy Chains: IgG, IgA, IgM, IgD, and IgE.
- Diagnosis: High levels of M protein in blood or urine can indicate multiple myeloma or other plasma cell tumors.
- Tests: Serum protein electrophoresis (SPEP) measures M proteins in blood samples.

For more detailed information, you can refer to the source: [Myeloma Protein (M Protein): What Is It? | MyMyelomaTeam](https://www.mymyelomateam.com/resources/the-rol...).

 This AI-generated response comes from MyMyelomaTeam and other selected sources. It is not a substitute for medical advice. Always ask your doctor about specific health concerns.

Myeloma Protein (M Protein): What Is It? | MyMyelomaTeam

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