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Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

What Is The Significance Of Free Light Chains?

A MyMyelomaTeam Member asked a question 💭
Raleigh, NC
September 14
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A MyMyelomaTeam Member

Ed I think free light chains are more likely to cause kidney problems if left untreated.

September 14
A MyMyelomaTeam Member

Free light chains are significant in the context of multiple myeloma for several reasons:

- Diagnosis: A serum free light chain (SFLC) assay can detect excess light chains in the blood, which is crucial for diagnosing light chain multiple myeloma. A serum free light chain ratio of 100 or more is one of the diagnostic Show Full Answer

Free light chains are significant in the context of multiple myeloma for several reasons:

- Diagnosis: A serum free light chain (SFLC) assay can detect excess light chains in the blood, which is crucial for diagnosing light chain multiple myeloma. A serum free light chain ratio of 100 or more is one of the diagnostic criteria.
- Prognosis: High levels of free light chains are associated with a poorer prognosis. People with a high SFLC score are likely to have a worse disease course.
- Monitoring: SFLC assays are used to monitor the disease's progression and response to treatment.

These tests help in early detection, assessing the severity, and managing the treatment of multiple myeloma.

September 14

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