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What Is The Difference Between Kappa And Lambda Light Chains

A MyMyelomaTeam Member asked a question 💭
Bend, OR
August 5
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A MyMyelomaTeam Member

In the context of light chain multiple myeloma:

- Kappa and Lambda Light Chains: These are two types of light chains that are part of immunoglobulins (antibodies). In light chain multiple myeloma, the body produces an excess of one type of light chain, either kappa or lambda
- Detection: A serum free light chain assay can Show Full Answer

In the context of light chain multiple myeloma:

- Kappa and Lambda Light Chains: These are two types of light chains that are part of immunoglobulins (antibodies). In light chain multiple myeloma, the body produces an excess of one type of light chain, either kappa or lambda.
- Detection: A serum free light chain assay can detect the levels of these light chains in the blood. In people with light chain multiple myeloma, there will be a much higher level of one type of light chain compared to the other.
- Clinical Significance: The imbalance between kappa and lambda light chains can help diagnose light chain multiple myeloma. A serum free light chain ratio of 100 or more is one of the diagnostic criteria.

For more detailed information, you can refer to the source: [Light Chain Multiple Myeloma: Your Ultimate Guide | MyMyelomaTeam](https://www.mymyelomateam.com/resources/light-c...).

August 5

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