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Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

I Have A Question About Pomalyst/dara..

A MyMyelomaTeam Member asked a question 💭
Elkhorn, NE

my husband has been on pomalyst for 1 year but seems to have sinus infections repeatedly...every 2 1/2 mo. anyone else have this issue - he always seemed to get a cold with a sinus issue before he had myeloma and I know pomalyst does effect the respiratory part of the body....we always seem to have to get a Zpak from the Dr. would taking more Fit. C help...don't always want to call the Dr. looking for ideas or suggestions.

August 12
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A MyMyelomaTeam Member

I take NONI to boost my immune system, and Zinc. Check out Dr Brandy’s book “Beat Back Cancer Naturally “. Dr Brandy has MM and his diet and supplements really help him.
Paula 🌹

August 12
A MyMyelomaTeam Member

Hi
I have been on pomalyst since end of November 2023. Ii haven’t been sick for a long time prior to being on pomalyst.. I started out with allergies then turned into a sinus infection. I went to a clinic on a Saturday and was prescribed an antibiotic
( doxycycline) for 7 days. I feel like I have a slight cold now. I am getting monthly IVIG infusions because my wbc is low along with my immunoglobulins and hemoglobin. Pomalyst is known to cause low wbc, rbc, and immunoglobulins.
I am also getting month Dara faspro injections. Before and when I was first diagnosed, I was getting a sinus infections monthly I would just get over it and I would get another one.
Does your husband get any IVIG? If not, maybe he should talk to his oncologist about it. Hope he feels better soon I know how miserable this can be.

August 12
A MyMyelomaTeam Member

It seems like you have a question about Pomalyst (pomalidomide) and possibly Darzalex (daratumumab). Here is some detailed information based on the knowledge base:

Pomalyst (Pomalidomide)
- Purpose: Approved by the FDA to treat multiple myeloma that has progressed after other therapies
- Combination: Often combined with Show Full Answer

It seems like you have a question about Pomalyst (pomalidomide) and possibly Darzalex (daratumumab). Here is some detailed information based on the knowledge base:

Pomalyst (Pomalidomide)
- Purpose: Approved by the FDA to treat multiple myeloma that has progressed after other therapies.
- Combination: Often combined with a corticosteroid, such as dexamethasone.
- Mechanism: An immunomodulator that modulates the immune system. It may prevent the growth of new blood vessels that supply tumors.
- Administration: Taken orally on days 1 through 21 in a 28-day cycle, in capsule form.
- Common Side Effects:
- Fatigue
- Low blood count
- Constipation
- Nausea
- Diarrhea
- Upper respiratory tract infections
- Back pain
- Fever
- Serious Side Effects:
- Liver failure
- Blood toxicity
- Tumor lysis syndrome
- Hypersensitivity
- Severe skin reactions

Darzalex (Daratumumab)
- Purpose: Approved by the FDA for treating multiple myeloma in people who have tried other therapies or are ineligible for autologous stem cell transplant.
- Combination: Often combined with other drugs such as Velcade, Pomalyst, or Revlimid, along with a corticosteroid.
- Mechanism: A monoclonal antibody designed to attach to myeloma cells, believed to work by killing myeloma cells directly and helping the immune system recognize and attack myeloma cells.
- Administration: Administered as an intravenous infusion.
- Common Side Effects:
- Infusion site reactions

For more detailed information, you can visit the respective pages on MyMyelomaTeam:
- [Pomalyst](https://www.mymyelomateam.com/treatments/pomalyst)
- [Darzalex](https://www.mymyelomateam.com/treatments/darzalex)

If you have any specific questions about these treatments, feel free to ask!

August 12

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