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My First Report Says “Monoclonal Gammopathy Seen With IgG And Lambda” What Does It Mean?

A MyMyelomaTeam Member asked a question 💭
Indian, AK

I have horrible back ache which radiates to legs and the pain keeps moving around from left to right leg. Sometimes even ribs. Doctor put me on Bortezomib and Dexa

July 17
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A MyMyelomaTeam Member

Hi Scott, Yes

July 17
A MyMyelomaTeam Member

You have M protein and it is IgG lambda. Are these results from a bone marrow biopsy?

July 17
A MyMyelomaTeam Member

In the context of multiple myeloma:

- Monoclonal Gammopathy: This refers to the presence of abnormal antibodies produced by a single clone of plasma cells. These antibodies are identical and are known as M proteins
- IgG: This is the most common type of antibody found in multiple myeloma. Almost half of people with Show Full Answer

In the context of multiple myeloma:

- Monoclonal Gammopathy: This refers to the presence of abnormal antibodies produced by a single clone of plasma cells. These antibodies are identical and are known as M proteins.
- IgG: This is the most common type of antibody found in multiple myeloma. Almost half of people with multiple myeloma have M protein that contains IgG.
- Lambda: This refers to the type of light chain protein associated with the antibody.

In summary, your report indicates that there is an abnormal production of IgG antibodies with lambda light chains, which is a characteristic seen in multiple myeloma.

July 17

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