I am fortunate to only experience neuropathy and itching. My neuropathy is now limited to numbness during a long treatment period of acupuncture, and itching is addressed with benedryl. I have tried Gabapentin, CBD, and CBD/THC blends which did not work for me. Sometimes Tylenol took a slight edge off neuropathy in my feet and hands, moisturizer on my hands and feet. I used kinesiology tape on my feet for the longest while effectively too. I generally avoid additional medications is just a personal preference.

Richard265
In Myeloma issue pain,lack of sleep ,tired is part of the problem we have to overcome,In the evening around 9 pm l always feel very sleepy and tired but I try to control to stay awake it will not help and l will wake up at around 2am and never sleep anymore. the reason that my body will be in pain or itchy and it happened 3 to 4 times in a week but after I had my breakfast I will feel very sleepy after I took all the medication and only l slept for just half an hour that all and the pain sometimes will come back.Can I say that MM giving us problem or it is a test for all of us.

What dosage of Dex are you taking? The new guidelines are reducing the amount significantly.

I have not tried CBD for pain and sleep problems but everything I have read seems to indicate that it could work for you, it does for some people depending on the cause of the pain. My doctor recently prescribed gabapentin to address my nerve issues (which do make it very difficult to sleep). I hope it works. Check with your doctors to see if it could help you.

Corticosteroids are notorious for disrupting sleep. When I changed doctors my new doctor took me off 'dex' and prescribed methylprednisolone (a/k/a Medrol) instead. Medrol has not affected my sleep nearly as much as dex.
Also, I understand that getting dex via infusion does not affect sleep as much as taking dex orally. Something to talk over with your oncologist.