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Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

In The Years Following ASCT Are There Repeating Cycles Of Remission, Relapse, Treatment, Remission, Relapse, Treatment, …?

A MyMyelomaTeam Member asked a question 💭
Chestertown, MD

If I have correctly understood the double blind, refereed scientific articles , material on the US NCI, NIH, and the long conversations with my MM team, post-ASCT (or not if you didn’t go through it) relapse is inevitable even if you have been on maintenance therapy, then one goes back to induction type treatment (CAR-T, bispecific, or something else) to achieve remission. Does this become a repeating cycle? With passage of time do these treatment, remission, relapse cycles become of shorter… read more

July 2
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A MyMyelomaTeam Member

From what I understand the rinse and repeat cycle is what we will experience. And studies show that the longer your initial remission the longer your overall survival. Each subsequent remission is shorter and shorter. I consider each remission a stay of execution and hope we can all get 9 of them like a cat.

July 2
A MyMyelomaTeam Member

Yes, in the years following an autologous stem cell transplant (ASCT) for multiple myeloma, it is common to experience repeating cycles of remission, relapse, and treatment. Here are some key points:

- Initial Remission: Most people respond well to their first-line therapy and achieve remission for about four years on Show Full Answer

Yes, in the years following an autologous stem cell transplant (ASCT) for multiple myeloma, it is common to experience repeating cycles of remission, relapse, and treatment. Here are some key points:

- Initial Remission: Most people respond well to their first-line therapy and achieve remission for about four years on average.
- Relapse: After the initial remission, most people will eventually relapse. Some may experience early relapses within a year.
- Subsequent Treatments: After a relapse, new treatment plans are developed, which may include restarting original therapy, another ASCT, or other medications.
- Multiple Relapses: It is typical to undergo periods of response to new medications followed by subsequent relapses.

For more detailed information, you can refer to the provided resources.

July 2

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