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Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Has Anyone Ever Undergone An Allogeneic Stem Cell Transplant. I Read That Although Riskier Than Autologous, This Has In Some Cases Cured MM.

A MyMyelomaTeam Member asked a question 💭
Hurricane, UT
May 22
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A MyMyelomaTeam Member

There was an older gentleman around my age, in the healing home I was staying in after my SCT. He told me he had a STC with a donor. He had side effects and was still being monitored closely by the hospital. He was staying put for awhile while I went home after two weeks. He felt like he was cured once he got to a certain point.

May 23
A MyMyelomaTeam Member

True an Allogeneic SCT is riskier because your body will likely want to reject the stem cells and a SCT doesn’t cure the MM but it does put it into remission.

May 23
A MyMyelomaTeam Member

My APN’s husband got a allo transplant from his mother and now has abnormal male karyotype. So he asked her is he turning female. lol. No.

May 23
A MyMyelomaTeam Member

Allogeneic transplant is a lot riskier. A lot more side effects. Graft vs host disease that can affect skin, eyes, GI tract and the liver. I believe Jack Aeilo a myeloma coach has an allogeneic transplant.

May 23
A MyMyelomaTeam Member

Yes, allogeneic stem cell transplants have been performed for multiple myeloma and, in some cases, they can indeed cure the disease. However, it's important to note that this type of transplant carries a significant risk of life-threatening side effects. Typically, it's considered for younger individuals with high-risk Show Full Answer

Yes, allogeneic stem cell transplants have been performed for multiple myeloma and, in some cases, they can indeed cure the disease. However, it's important to note that this type of transplant carries a significant risk of life-threatening side effects. Typically, it's considered for younger individuals with high-risk, relapsed myeloma, especially when an autologous stem cell transplant has failed. The potential for curing myeloma comes from the graft-versus-myeloma effect, where the donor's immune cells may help attack the cancer cells. However, the risk of graft-versus-host disease (GVHD), where the donor cells attack the recipient's body, often outweighs this benefit.

May 22

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