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MGUS And Progression To Myeloma

A MyMyelomaTeam Member asked a question 💭
Sarsota FL

How long does it take for MGUS to progress to Multiple Myeloma

May 2
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A MyMyelomaTeam Member

Hi Chris,
It depends on your type, IgG, IgA or others. Kappa vs Lambda. It also depends on whether you have translocations, deletions or additions. I have IgA Kappa which is higher risk to progress. I also have t(14;16) which is rare and high risk once I am diagnosed with MM. I am currently Smoldering. I was told when I had MGUS that progression could take 20-30 years, but after doing research, I saw my type progresses quicker. Diagnosed with MGUS 2020. SMM 2023. MM is still pending. Some people with MGUS never progress and have no symptoms. I had symptoms and severe osteoporosis. I recommend Dr Brandy’s book “Beat Back Cancer Naturally” to help you make changes in your diet and what supplements to take. My good numbers went up and bad numbers went down after taking some of the supplements he recommends. If you can get your immune system, which is in your gut, to get as heathy as you can, you may be able to keep it from progressing.
Paula🌹

May 2
A MyMyelomaTeam Member

Thank you for the tips Pbldini ,& the book tip. Will look it up

May 2
A MyMyelomaTeam Member

After watching some of Dr Brandy’s talks online, I was amazed at how smart he is. He has MM too and is doing quite well.

May 2
A MyMyelomaTeam Member

Monoclonal gammopathy of undetermined significance (MGUS) is a condition where plasma cells produce an abnormal protein, but it is generally benign and symptom-free. However, there is a concern among those diagnosed with MGUS about its potential progression to multiple myeloma, a type of blood cancer. Here are key points Show Full Answer

Monoclonal gammopathy of undetermined significance (MGUS) is a condition where plasma cells produce an abnormal protein, but it is generally benign and symptom-free. However, there is a concern among those diagnosed with MGUS about its potential progression to multiple myeloma, a type of blood cancer. Here are key points regarding MGUS and its progression to multiple myeloma:

1. **Progression Risk**: While MGUS itself is noncancerous and often causes no symptoms, it can progress to multiple myeloma or other serious conditions. The progression is not inevitable and varies among individuals.

2. **Monitoring and Follow-Ups**: Due to the risk of progression, regular monitoring is crucial. Doctors typically recommend blood tests and may adjust the frequency of follow-ups based on the assessed risk level of the individual.

3. **Research and Treatment**: Currently, there is no proven way to prevent the progression of MGUS to multiple myeloma. However, ongoing research and clinical trials are exploring treatments that could potentially slow or stop this progression.

4. **Personal Experiences**: Some members of the MyMyelomaTeam community have shared their experiences with MGUS progressing to multiple myeloma, highlighting the importance of ongoing monitoring and early treatment intervention.

Understanding these aspects can help individuals with MGUS manage their condition proactively with their healthcare provider.

May 2

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