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What Does A Diagnosis Of MGUS Mean And Does It Progress To Myeloma

A MyMyelomaTeam Member asked a question 💭
Sarsota FL
April 28
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A MyMyelomaTeam Member

No it doesn't mean you will get myeloma. My older sister has had MGUS for 10 years. She is fine. I'm the one with the high risk myeloma. You can Google the stats on MGUS going into myeloma. The great news is they caught yours early. I would recommend you see a good oncologist and even a myeloma Specialist would be a good idea. My sister gets a myeloma panel every 6 months. She has never had a bone marrow biopsy.

April 28
A MyMyelomaTeam Member

A diagnosis of Monoclonal Gammopathy of Undetermined Significance (MGUS) indicates the presence of abnormal protein (monoclonal protein, or M protein) in the blood, which is produced by plasma cells. It's important to note that MGUS is a noncancerous condition and does not involve a tumor. However, it requires monitoring Show Full Answer

A diagnosis of Monoclonal Gammopathy of Undetermined Significance (MGUS) indicates the presence of abnormal protein (monoclonal protein, or M protein) in the blood, which is produced by plasma cells. It's important to note that MGUS is a noncancerous condition and does not involve a tumor. However, it requires monitoring because it can potentially progress to more serious conditions like multiple myeloma, although the risk is relatively low.

Here's what you need to know about the progression:
- **Progression Rate**: People with MGUS have about a 1% chance per year of their condition progressing to multiple myeloma.
- **Monitoring**: Regular blood tests and follow-ups are crucial to detect any signs of progression early. This allows for timely intervention and management.

Most individuals with MGUS live without it ever developing into multiple myeloma, but regular check-ups are essential to manage and monitor the condition effectively.

April 28

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