my husband has been fighting MM for 10 years. Hes been on several drugs. Polmalyst was by far the one he would prefer to stay on. The only side effect was diahrea. Other than that he felt good. It helped keep him in remission for 2 years,

I too have Kappa Light Chain MM; after 6 months on Revlimid and Velcade , plus Dexamethasone I am now one year in remission. Velcade gave me a rash at injection site. Dexamethasone gave me a terrible rash over large sections of my skin . Dr eliminated Velcade and Dexamethasone and reduced Revlimid to 10 mg and I remain with this protocol . If I watch my diet I can control my tummy issues to be “normal”.
I have chosen to not do a SCT at this time, and if I relapse will make that decision at that time.
Have already discussed changes in treatment if I relapse with my oncologist. I live with a “feeling good now, don’t worry unless it changes” attitude .
Wishing everyone well….

I've been on this MM journey since June of 2018 and have graduated Revlimid to becoming a Pomalyst user. I experience the opposite effects, Constipation. To counter that, I take one generic stool softener, once a day. They keep me running, as close to normal as I remember it to be.

If you are not having fatigue you most likely will.

Thanks, Ken....Lots of experience with that one :-(