Talvey, also known by its drug name talquetamab, is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat relapsed or refractory multiple myeloma in adults who have already tried at least four lines of therapy. These previous therapies must include:
- A proteasome inhibitor
- An Show Full Answer
Talvey, also known by its drug name talquetamab, is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat relapsed or refractory multiple myeloma in adults who have already tried at least four lines of therapy. These previous therapies must include:
- A proteasome inhibitor
- An immunomodulatory agent
- An anti-CD38 monoclonal antibody
Talvey is a bispecific T-cell engager. It consists of a genetically engineered protein, or antibody, that targets the GPRC5D protein on B cells — including myeloma cells — and the CD3 protein on T cells. Talvey works by prompting T cells to kill myeloma cells.
Administration:
- Talvey is given as a subcutaneous (under the skin) injection.
- It comes in a single-dose vial.
- The correct dosage schedule is determined by a doctor, and monitoring in the hospital may be required after initial doses.
Common Side Effects:
- Cytokine release syndrome (a potentially fatal inflammatory reaction causing severe neurological symptoms such as hallucinations and tremors)
- Skin problems, rash
- Fatigue
- Weight loss
- Dry mouth
- Trouble swallowing
- Headache
- Musculoskeletal pain
- Low blood pressure
- Diarrhea
- Upper respiratory infections
- Fever
- Changes to the sense of taste
Rare but Serious Side Effects:
- Oral toxicity
- Infections
- Low levels of certain blood cells
- Skin toxicity and rash
- Liver toxicity
- Potential fetal harm for pregnant people
For more details, you can visit:
- Talvey — Janssen Biotech: [https://www. talvey.com](https://www.talvey.com)
- Talvey — Drugs.com: [https://www.drugs.com/talvey.html](https://www....
July 19, 2024
Continue with Facebook
Sign up with your email
