Tests that reveal MRD (Minimal Residual Disease) negativity or positivity include:

- Polymerase Chain Reaction (PCR): This technique creates many copies of a small part of a gene to detect specific genes or gene changes
- Next-Generation Sequencing (NGS): This method reads many different genes within a cell sample and is Show Full Answer

Tests that reveal MRD (Minimal Residual Disease) negativity or positivity include:

- Polymerase Chain Reaction (PCR): This technique creates many copies of a small part of a gene to detect specific genes or gene changes.
- Next-Generation Sequencing (NGS): This method reads many different genes within a cell sample and is more sensitive than PCR. The FDA-approved clonoSEQ test is an example of an NGS test used for MRD detection.
- Flow Cytometry: This test analyzes bone marrow or blood samples to determine the number of cancerous cells.
- Imaging Tests (PET/CT scans): These can detect myeloma cells outside the bone marrow.

These tests help determine if a person is MRD-positive (some remaining myeloma cells) or MRD-negative (no detectable myeloma cells).

 This AI-generated response comes from MyMyelomaTeam and other selected sources. It is not a substitute for medical advice. Always ask your doctor about specific health concerns.

What Is Minimal Residual Disease (MRD) in Myeloma? | MyMyelomaTeam