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Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Does Anyone Have A High Risk Mutation That Cause The Cancer To Come Out Of Remission Much Quicker?

A MyMyelomaTeam Member asked a question 💭
Tinton Falls, NJ

I was just told that I have a high risk mutation known as translocation 1416 that causes the cancer to come out of remission quicker. I thought I was getting some good news about it being stage 2 but unfortunately the high risk mutation has a huge effect on everything apparently.

July 20, 2019
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A MyMyelomaTeam Member

I also have trisomy 9 and translocation of 11:14. I don't panic as bad as I use to. You for sure need a world class myeloma specialist when you have high risk mutations. Yes, getting diagnosed with MM was horrible. Then I started reading my labs and freaked out again. I know I'm getting good treatment and I ask God to heal me. Other than that, I try not to think about my crazy chromosomes😉

July 20, 2019 (edited)
A MyMyelomaTeam Member

Yes, I have deletion of TP53. It is associated with increased proliferation and a less favorable prognosis. I had the transplant. I'm on Pomalyst, dexamethasone and Darzalex. My doctors tell me after 3 years of aggressive maintenance, I hopefully will be able to be treated as standard risk.😇

July 20, 2019
A MyMyelomaTeam Member

Thank you for your response

September 17, 2019

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