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Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

My IgG And IgA Are Normal But, My IgM Is Low. How Does This Result Impact My Response To Vaccines? How Can I Rectify This Situation?

A MyMyelomaTeam Subscriber asked a question 💭

My current MM maintenance treatment is taking 10 mcg of Revlmid each day. My M proteins have been non-detectable for about 14 months.

December 15, 2024
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IgG and IgA Antibodies in Myeloma: Which Is More Aggressive? Read Article...
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Low IgM levels can affect your immune response to certain vaccines, particularly those that rely on IgM for initial immune defense. However, since your IgG and IgA levels are normal, your body may still mount a sufficient response to most vaccines. Your maintenance treatment with Revlimid (lenalidomide) could also influence Show Full Answer

Low IgM levels can affect your immune response to certain vaccines, particularly those that rely on IgM for initial immune defense. However, since your IgG and IgA levels are normal, your body may still mount a sufficient response to most vaccines. Your maintenance treatment with Revlimid (lenalidomide) could also influence your immune system's function.

To address this, consult your doctor about strategies like timing vaccinations when your immune system is stronger or considering additional supportive treatments like IVIG. IVIG can help bolster your immune system by providing donor antibodies, which may help protect against infections. Always discuss any changes with your healthcare provider.

December 15, 2024

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