Are you asking about CAR-T cell therapy for multiple myeloma? Here is some detailed information based on my knowledge base:

CAR-T Cell Therapy for Multiple Myeloma
- What It Is: CAR-T cell therapy involves genetically engineering a person's T cells to target and attack myeloma cells. The T cells are modified to express Show Full Answer

Are you asking about CAR-T cell therapy for multiple myeloma? Here is some detailed information based on my knowledge base:

CAR-T Cell Therapy for Multiple Myeloma:
- What It Is: CAR-T cell therapy involves genetically engineering a person's T cells to target and attack myeloma cells. The T cells are modified to express chimeric antigen receptors (CARs) that can recognize and bind to specific proteins on cancer cells.
- Process:
- T Cell Collection: T cells are harvested from the patient.
- Genetic Modification: The T cells are modified in a lab to express CARs.
- Expansion: The modified T cells are grown in large numbers.
- Infusion: The CAR-T cells are infused back into the patient.
- Preparation: Before receiving CAR-T cells, patients often undergo lymphodepletion, a chemotherapy treatment to make room for the new T cells.
- Duration: The entire process, from T cell collection to infusion, can take up to three weeks.

Carvykti (Ciltacabtagene Autoleucel):
- Approval: Carvykti is FDA-approved for treating relapsed or refractory multiple myeloma in adults who have tried at least four lines of therapy, including a proteasome inhibitor, an immunomodulatory agent, and an anti-CD38 monoclonal antibody.
- Mechanism: Carvykti targets the B-cell maturation antigen (BCMA) on myeloma cells.
- Type: It is a type of CAR-T cell therapy made from the patient's own T cells.

For more detailed information, you can visit the following links:
- Carvykti: [Carvykti (Ciltacabtagene autoleucel) for Myeloma](https://www.mymyelomateam.com/treatments/carvykti)
- CAR-T Cell Therapy: [CAR-T Cell Therapy for Multiple Myeloma: What Is It?](https://www.mymyelomateam.com/resources/car-t-c...)

If you have any more specific questions, feel free to ask!

 This AI-generated response comes from MyMyelomaTeam and other selected sources. It is not a substitute for medical advice. Always ask your doctor about specific health concerns.

CAR-T Cell Therapy for Multiple Myeloma: What Is It? | MyMyelomaTeam

Carvykti (Ciltacabtagene autoleucel) for Myeloma | MyMyelomaTeam