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Anyone With 11:14 Been Treated With Venetoclax? What Was Your Experience?

A MyMyelomaTeam Member asked a question 💭
Valdez, AK

I have 11:14 and 1q gain . Very slow response to standard 4 drug treatment

October 23
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A MyMyelomaTeam Member

Hi Alicia, I have 11:14 and p53/17 p deletion. So I was told Ventoclax would be my next treatment when I relapse. My concern is that the latest 2 clinical trials with Ventoclax did not show a great response and people died of infections. So, it's still not FDA approved for myeloma. Only in clinical trials. They are thinking it works well with amyloidosis. Could you please keep me updated on what you specialist is saying. I am also interested in what you are calling a slow response. I also seen to response slowly to treatments. But, thank the Lord, I do respond to treatment. I've had myeloma since 2017. Actually a long time before I knew I had it. Anyway, I have read that 11:14 can be slow to respond. I have also read that 11:14 are slow responders, but can do ok anyway. What are your thoughts?

October 24
A MyMyelomaTeam Member

I have the same type of Myeloma,however I responded so well my doctors are surprised. I had a SCT in May of 2021, I just take revlimid 10mg , I take a break for 12 days only because it makes me tired and I need my immune system to recover. I think everyone is so different in responses . I wish you all well and I know things can change in a moment

October 24
A MyMyelomaTeam Member

I always feel better knowing plan B…and C!

October 26
A MyMyelomaTeam Member

My specialist says there is always a plan b

October 25 (edited)
A MyMyelomaTeam Member

That's interesting Donna that you have your next line of treatment mapped out. One of the things my oncologist says is wait 6-12 months and the available treatments will be completely different and new. So I'm also just waiting for the next relapse and then will decide what new (or even old) treatments are available.

October 24

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