Connect with others who understand.

Sign up Log in
Resources
About MyMyelomaTeam
Powered By
Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

This Looks Like Good News

A MyMyelomaTeam Member asked a question 💭
San Jose, CA

https://myelomaresearchnews.com/news/fda-approv...

FDA approves Sarclisa regimen as first-line treatment for myeloma
FDA approves Sarclisa regimen as first-line treatment for myeloma
September 30
•
View reactions
A MyMyelomaTeam Member

Thanks for this information and providing a link to the article. So some quick research by myself:
Sarclisa (isatuximab) is a monoclonal antibody therapy developed by Sanofi to treat myeloma. Sarclisa targets the CD38 protein present on myeloma cells and promotes their death.
AND
The decision makes Sarclisa the first anti-CD38 therapy in combination with the standard VRd regimen to be approved for newly diagnosed patients who are ineligible for an autologous stem cell transplant. While another anti-CD38 therapy, called Darzalex, is also approved for this indication, it is used with other treatment combinations but not with VRd.

This statement is not true. Darzalex IS now being used with VRd for induction therapy.

It appears this is very similar to the use of Darzalex for front line induction therapy. They also mention the use of Sarclisa for relapsed and refractory MM. it appears the MM community has confidence in both of these drugs that they will not cause major side effects or inhibit the functionality of VRd and are adding these drugs into induction therapy.

October 3 (edited)
A MyMyelomaTeam Member

Hi Ripnlips, just another tool in our toolbox in this fight for our lives.

October 4
A MyMyelomaTeam Member

Hi Rick this Looks very promising and great. It is back by FDA!

October 2

Related content

View All

This Looks Very Promising

A MyMyelomaTeam Member asked a question 💭
San Jose, CA

I Have A Bloating Of My Stomach Past Two Week. Lot Of Gas After Eating Food. My Stomach Looks Like A Pengent Woman. Any Help

A MyMyelomaTeam Member asked a question 💭
bangalore

Revlimid

A MyMyelomaTeam Member asked a question 💭
San Jose, CA
Continue with Facebook
Continue with Google
By joining, you accept our Terms of Use, and acknowledge our collection, sharing, and use of your data in accordance with our Health Data Policy and Privacy policies.Your privacy is our priority Lock Icon
Already a Member? Log in