CAR-T cell therapy is a promising treatment for multiple myeloma, especially for those with advanced stages of the disease. Here are some key points:
How CAR-T Cell Therapy Works
- Collection: T cells are collected from the person with myeloma.
- Modification: These T cells are genetically modified in a lab to better Show Full Answer
CAR-T cell therapy is a promising treatment for multiple myeloma, especially for those with advanced stages of the disease. Here are some key points:
How CAR-T Cell Therapy Works:
- Collection: T cells are collected from the person with myeloma.
- Modification: These T cells are genetically modified in a lab to better recognize and attack cancer cells.
- Infusion: The modified T cells are returned to the body through an IV infusion after a round of chemotherapy (lymphodepletion).
Potential Side Effects:
- Common side effects include:
- Infections
- Muscle aches
- Diarrhea
- Nausea
- Swelling
- Fever
- Cough
- Headache
- Loss of appetite
- Cytokine Release Syndrome (CRS): A condition that can develop post-therapy, involving a large release of cytokines, which are immune system messengers.
Effectiveness:
- CAR-T cell therapy has shown to be effective for many, even when other treatments have failed.
- In clinical trials, 2 out of 3 participants were in remission for at least one year.
- However, it does not work for everyone, and cancer can sometimes return.
Experience Sharing:
- MyMyelomaTeam is a social network where over 11,000 people with multiple myeloma and their loved ones share their experiences, ask questions, and offer support.
Considerations:
- Discuss thoroughly with your doctor about the risks and benefits.
- Treatments are available to manage many of the side effects.
- The therapy is only available at certified locations due to the need for specialized care.
For more personal experiences and support, consider joining MyMyelomaTeam to connect with others who understand life with multiple myeloma.
August 10