Fatigue is a common symptom in people with multiple myeloma. Here are some key points about fatigue related to multiple myeloma:

### Causes of Fatigue
1. Anemia:
- Myeloma cells interfere with bone marrow function, leading to a shortage of erythrocytes (red blood cells).
- Symptoms include rapid heartbeat, swollen Show Full Answer

Fatigue is a common symptom in people with multiple myeloma. Here are some key points about fatigue related to multiple myeloma:

### Causes of Fatigue:
1. Anemia:
- Myeloma cells interfere with bone marrow function, leading to a shortage of erythrocytes (red blood cells).
- Symptoms include rapid heartbeat, swollen legs, dizziness, headaches, chills, and decreased libido.

2. Cytokines:
- High levels of cytokines, small proteins released by T lymphocytes, can cause fatigue.
- Cytokines can cause cancer cells to grow and spread, contributing to fatigue.

3. Pain:
- Pain from multiple myeloma can lead to fatigue.
- The physical effects and emotional turmoil associated with the diagnosis can compound fatigue.

4. Treatments:
- Chemotherapy, corticosteroids, and radiation therapy can all cause fatigue.
- Chemotherapy side effects include insomnia, mood changes, muscle wasting, nausea, and vomiting.
- Corticosteroids can initially cause sleeplessness followed by a "crash" leading to fatigue.
- Radiation therapy can cause fatigue, which may worsen over time and last up to four weeks after treatment.

### Managing Fatigue:
1. Exercise:
- Regular, light exercise such as walking or low- to moderate-intensity resistance and aerobic training can help reduce fatigue.

2. Routine Activities:
- Keeping up with routine daily activities can combat fatigue and stress.

3. Medication Adjustments:
- Taking medication at night rather than in the morning can help reduce drowsiness.

4. Medical Help:
- Consult your health care team for strategies to manage fatigue.
- Treatment for anemia can also help improve energy levels.

Fatigue from multiple myeloma, also known as cancer-related fatigue, cannot be resolved with rest and can significantly impact quality of life.

 This AI-generated response comes from MyMyelomaTeam and other selected sources. It is not a substitute for medical advice. Always ask your doctor about specific health concerns.

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