Ok. I hear you. What this looks like is the defective gene being passed down generations and may continue until someone is told not to have children or a cure is found whichever comes first.

I would think this is somewhat rare and environmental is still the main cause. But environmental may include getting too much sun and having a predisposition to MM.

Thank you for your response!

So far I was the youngest at diagnosis, but longest living post-diagnosis. My brother was diagnosed almost a year after me, but died less than 2 months after his SCT. I will be 4years post SCT May 21 and have had no medications or relapses for MM in almost 2 1/2 years. So there is obviously tremendous variation, even within families with strong MM prevalence, in how this disease affects individuals.

I am sure there are environmental issues that affect the possibility of developing multiple myeloma, as with other cancers. My situation is different I think and I believe may indicate genetic transference of multiple myeloma. My great grandmother was raised in England and died of multiple myeloma. My mother (her granddaughter) was born and raised in Toronto and died of multiple myeloma. My brother was born on Toronto and, like me, was primarily raised in eastern ontario and he died of multiple myeloma. I was born in Cornwall Ontario, raised as my brother was geographically, and I have multiple myeloma.
Go figure, right?

It’s possible to be hereditary but more likely environmental factors that all three were exposed to in whatever geographic area they lived in. Did they all drink the same well water? Was there a chemical plant nearby? Did Pop use chlordane for termites back in the day? You see where I’m going.