I have been getting B12 shots for the last few months with no change in my fatigue levels. I did read recently that Revlimid does have a negative effect on B12 levels. So since I am seeing my oncologist tomorrow, it is on the list of questions I will ask. I have been on Revlimid for 4 1/2 years starting at 25mg and now down to 10mg.

The injections are supposed to help with that.

Started taking OTC 1000 mg of B12 as I experience heavy fatigue. Don't quite have anemia so unsure if it's even Myeloma related. Cytokines?

I haven’t had the B shot but wonder if it helps??

I have not noticed any change