Kyprolis (Carfilzomib) is a medication approved by the U.S. Food and Drug Administration (FDA) to treat multiple myeloma in people who have tried other therapies. It is often combined with a corticosteroid and other drugs such as Revlimid in specific chemotherapy regimens. Kyprolis is administered as an intravenous infusion Show Full Answer
Kyprolis (Carfilzomib) is a medication approved by the U.S. Food and Drug Administration (FDA) to treat multiple myeloma in people who have tried other therapies. It is often combined with a corticosteroid and other drugs such as Revlimid in specific chemotherapy regimens. Kyprolis is administered as an intravenous infusion and is a member of a class of drugs called proteasome inhibitors, which work by interfering with cell division.
Common side effects include:
- Anemia
- Fatigue
- Fever
- Nausea
- Diarrhea
- Cough
- Cold or flu symptoms
- Trouble breathing
- Swelling in the extremities
Rare but serious side effects include:
- Heart failure
- Kidney failure
- Tumor lysis syndrome
- Lung toxicity
- Hypertension
- Bleeding in the lungs, brain, or gastrointestinal system
- Fetal harm in pregnant women
For more details, you can visit the Kyprolis page on MyMyelomaTeam: [Kyprolis (Carfilzomib) for Myeloma](https://www.mymyelomateam.com/treatments/kyprolis).
July 21, 2024
My husband had Kyprolis as first line of treatment. It's less likely to cause neuropathy, but more likely to cause heart issues. My husband did, eventually,
Have heart rhythm issues, but he had a history of Afib. He was then switched to Valcaide and had no issues with neuropathy, It's usually used as a second line of treatment, and it has been a miracle drug for many.
January 23, 2024
So did they switch you to a different drug? I will only be having it every other week. Not sure that will make a difference.
January 23, 2024
I had no heart issues before that
And it happened about 3 hours after
January 23, 2024
I had 2 treatments
And my heart went into afib both times.
January 23, 2024