No, smoldering multiple myeloma (SMM) is not the same as monoclonal gammopathy of undetermined significance (MGUS). Here are the key differences:

- MGUS:
- Mildest type of plasma cell disorder.
- Noncancerous and doesn't cause symptoms.
- Lower levels of abnormal plasma cells and M protein.

- SMM
- Intermediate Show Full Answer

No, smoldering multiple myeloma (SMM) is not the same as monoclonal gammopathy of undetermined significance (MGUS). Here are the key differences:

- MGUS:
- Mildest type of plasma cell disorder.
- Noncancerous and doesn't cause symptoms.
- Lower levels of abnormal plasma cells and M protein.

- SMM:
- Intermediate level of plasma cell disorder between MGUS and multiple myeloma.
- Higher levels of plasma cells and M protein than MGUS but lower than multiple myeloma.
- Noncancerous and doesn't cause symptoms but has a higher risk of progressing to multiple myeloma.

Both conditions can potentially progress to multiple myeloma, but SMM has a higher risk of progression compared to MGUS.

 This AI-generated response comes from MyMyelomaTeam and other selected sources. It is not a substitute for medical advice. Always ask your doctor about specific health concerns.

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