Yes. Your kappa is one thing. But to really know if you are progressing the best accuracy is biopsy. I'm between 30 and 40 percent,and smoldering there for a long time. Definitely get a biopsy. Hang in there. God bless.

Toni,
Have you had a bone marrow biopsy? Are you working with a MM Specialist? Are your plasma cells under 10%? Do you know what your M spike is? It is good that you don’t have bone involvement. Have you had a DEXA scan for osteoporosis? The bone marrow biopsy will tell you if you have translocations, deletions, gain, or amplifications. Check out Multiplemyelomahub.com. “The IMWG 2/20/20 risk stratification model for smoldering multiple myeloma.” Serum M-Protein>2g/dl, serum free light chain ratio >20, Bone marrow plasma cells infiltration >20%. Not just one thing is looked at, so be aware of the others.
Paula 🌹

In January 2023 my light chains were 2447. Scary number. They are now in the normal range. Started treatment in Feb with Revlimid /Dex and Dara shots. Now my # is 13. Huge drop. Love that it’s working. I have no symptoms at this point. Was diagnosed smoldering in 2021.. wish all the best to you

Toni,
I have SMM. If I had not changed Doctors and had another bone marrow biopsy, I may not have known I progressed from MGUS to SMM.
Paula

Thanks Brad
I will ask my consultant about having a biopsy when I speak with him in November.
Have a good day 😊