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BM Biopsy & Transplant

A MyMyelomaTeam Member asked a question 💭
Dallas, TX

Can anyone share what their Bone Marrow Biopsy results were before or after transplant, if it was done. I am looking for % of the marrow filled with myeloma cells. Did you do any MRD testing before the transplant?

September 5, 2023
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A MyMyelomaTeam Member

My marrow was over 95% myeloma cells at diagnosis. Yes they did MRD testing. I didn't understand why at first since I was obviously positive. Now I understand it was to get my myeloma's genetic blue print to see how it changes over time. Anyway, my bone marrow was still 20-30% myeloma cells after induction in May 2017. After some setbacks I had a transplant Dec 2017. After transplant, February 2018, my marrow was less than 5% flow cytometry still showed presence of myeloma cells. My first MRD test was 117,448 clonal cells per million. My last MRD test, 11/04/2022 was 74 clonal cells per million. I get another BMB October 30th. I'm hoping it's still coming down. I hope this answers your question🥰💕 God is good 😉

September 5, 2023
A MyMyelomaTeam Member

Yes. Thank you!
This seems to be a "clean" marrow, apparently with no myeloma. When was this done? After first or second transplant? Did they tell you if you are in remission and if so, what degree/level of remission?
Please note - I am not an expert, I have just read several papers and most of my knowledge is based on Google and its AI.
Thank you, again.

September 5, 2023
A MyMyelomaTeam Member

Before SCT 85%

September 8, 2023
A MyMyelomaTeam Member

For sure!

September 8, 2023
A MyMyelomaTeam Member

Yes Sam. Thanks for your response. Doc used the term “half” loosely. 1.3-2.5 from previous 3.9 in vertebral bodies is roughly 50%. I see doc tomorrow morning to find out new regimen. Will keep all interested parties updated. Everyone is interested, right. lol

September 7, 2023

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