Certainly, Keith! Here are the pros and cons of Darzalex and Pomalyst based on the information in the knowledge base:

Darzalex (Daratumumab)
Pros
- Mechanism: Darzalex is a monoclonal antibody that targets myeloma cells, helping the immune system recognize and attack them.
- Combination Therapy: Often combined with other Show Full Answer

Certainly, Keith! Here are the pros and cons of Darzalex and Pomalyst based on the information in the knowledge base:

Darzalex (Daratumumab)
Pros:
- Mechanism: Darzalex is a monoclonal antibody that targets myeloma cells, helping the immune system recognize and attack them.
- Combination Therapy: Often combined with other drugs like Velcade, Pomalyst, or Revlimid, along with a corticosteroid, enhancing its effectiveness.
- Administration: Administered as an intravenous infusion.

Cons:
- Common Side Effects: Infusion site reactions, low blood cell counts, fatigue, dizziness, fever, chills, cough, cold or flu symptoms, nausea, vomiting, diarrhea, constipation, back pain, joint pain, muscle spasms, peripheral neuropathy, and swelling in the extremities.
- Serious Side Effects: Severe infusion site reactions and low blood cell counts.

Pomalyst (Pomalidomide)
Pros:
- Mechanism: Pomalyst is an immunomodulatory drug that helps the immune system attack myeloma cells and inhibits their growth.
- Combination Therapy: Often used in combination with other treatments to enhance its effectiveness.

Cons:
- Common Side Effects: Fatigue, diarrhea, constipation, nausea, back pain, and fever.
- Serious Side Effects: Liver failure, blood toxicity, tumor lysis syndrome, hypersensitivity, and severe skin reactions.

For more details, you can visit the respective pages:
- [Darzalex](https://www.mymyelomateam.com/treatments/darzalex)
- [Pomalyst](https://www.mymyelomateam.com/treatments/pomalyst)

Hope this helps!

 This AI-generated response comes from MyMyelomaTeam and other selected sources. It is not a substitute for medical advice. Always ask your doctor about specific health concerns.

Pomalyst (Pomalidomide) for Myeloma | MyMyelomaTeam

Darzalex (Daratumumab) for Myeloma | MyMyelomaTeam